Histamine Receptor H1 (HRH1) (Middle Region) Peptide
HRH1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN978241
Aperçu rapide pour Histamine Receptor H1 (HRH1) (Middle Region) Peptide (ABIN978241)
Antigène
HRH1
(Histamine Receptor H1 (HRH1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- ENPKGDAKKP GKESPWEVLK RKPKDAGGGS VLKSPSQTPK EMKSPVVFSQ
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-HRH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HRH1 (Histamine Receptor H1 (HRH1))
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Sujet
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Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: H1-R, hisH1
Protein Size: 487 -
Poids moléculaire
- 56 kDa
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ID gène
- 3269
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NCBI Accession
- NM_000861, NP_000852
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UniProt
- P35367
Antigène
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